In cerebrospinal fluid during bacterial meningitis, which pattern is typically observed?

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Multiple Choice

In cerebrospinal fluid during bacterial meningitis, which pattern is typically observed?

Explanation:
In bacterial meningitis, the CSF changes reflect acute infection and inflammation of the meninges. Glucose in the CSF is typically low because bacteria (and activated white cells) consume glucose, and the blood–brain barrier disruption slows glucose entry. Protein rises due to leakage of plasma proteins into the CSF from inflamed vessels. The cell count shows neutrophil predominance, as neutrophils are the primary responders in acute bacterial infections. Opening pressure is usually elevated because of inflammatory swelling and increased CSF production. So the pattern of decreased glucose, increased protein, neutrophil predominance, and higher pressure is the classic CSF finding in bacterial meningitis.

In bacterial meningitis, the CSF changes reflect acute infection and inflammation of the meninges. Glucose in the CSF is typically low because bacteria (and activated white cells) consume glucose, and the blood–brain barrier disruption slows glucose entry. Protein rises due to leakage of plasma proteins into the CSF from inflamed vessels. The cell count shows neutrophil predominance, as neutrophils are the primary responders in acute bacterial infections. Opening pressure is usually elevated because of inflammatory swelling and increased CSF production. So the pattern of decreased glucose, increased protein, neutrophil predominance, and higher pressure is the classic CSF finding in bacterial meningitis.

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